Ferrous iron-dependent drug delivery enables controlled and selective release of therapeutic agents...
Ferrous iron-dependent drug delivery enables controlled and selective release of therapeutic agents in vivo
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The precise targeting of cytotoxic agents to specific cell types or cellular compartments is of significant interest in medicine, with particular relevance for infectious diseases and cancer. Here, we describe a method to exploit aberrant levels of mobile ferrous iron (Fe ᴵᴵ) for selective drug delivery in vivo. This approach makes use of a 1,2,4-t...
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Full title
Ferrous iron-dependent drug delivery enables controlled and selective release of therapeutic agents in vivo
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Record Identifier
TN_cdi_proquest_miscellaneous_1449269995
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1449269995
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1312782110
