Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction
Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction
About this item
Full title
Author / Creator
Moy, Lily Y , Jia, Yanlin , Caniga, Michael , Lieber, Gissela , Gil, Malgorzata , Fernandez, Xiomara , Sirkowski, Erich , Miller, Richard , Alexander, Jessica P , Lee, Hyun-Hee , Shin, John D , Ellis, J Michael , Chen, Hongmin , Wilhelm, Alan , Yu, Hongshi , Vincent, Stella , Chapman, Richard W , Kelly, Nancy , Hickey, Emily , Abraham, William M , Northrup, Alan , Miller, Thomas , Houshyar, Hani and Crackower, Michael A
Publisher
United States: American Thoracic Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Thoracic Society
Subjects
More information
Scope and Contents
Contents
Spleen tyrosine kinase (SYK) is a key activator of signaling pathways downstream of multiple surface receptors implicated in asthma. SYK function has been extensively studied in mast cells downstream of the high-affinity IgE receptor, FcεR1. Preclinical studies have demonstrated a role for SYK in models of allergic inflammation, but a role in airwa...
Alternative Titles
Full title
Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction
Authors, Artists and Contributors
Author / Creator
Jia, Yanlin
Caniga, Michael
Lieber, Gissela
Gil, Malgorzata
Fernandez, Xiomara
Sirkowski, Erich
Miller, Richard
Alexander, Jessica P
Lee, Hyun-Hee
Shin, John D
Ellis, J Michael
Chen, Hongmin
Wilhelm, Alan
Yu, Hongshi
Vincent, Stella
Chapman, Richard W
Kelly, Nancy
Hickey, Emily
Abraham, William M
Northrup, Alan
Miller, Thomas
Houshyar, Hani
Crackower, Michael A
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1464495091
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1464495091
Other Identifiers
ISSN
1044-1549
E-ISSN
1535-4989
DOI
10.1165/rcmb.2013-0200OC