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Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction

Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1464495091

Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction

About this item

Full title

Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction

Publisher

United States: American Thoracic Society

Journal title

American journal of respiratory cell and molecular biology, 2013-12, Vol.49 (6), p.1085-1092

Language

English

Formats

Publication information

Publisher

United States: American Thoracic Society

More information

Scope and Contents

Contents

Spleen tyrosine kinase (SYK) is a key activator of signaling pathways downstream of multiple surface receptors implicated in asthma. SYK function has been extensively studied in mast cells downstream of the high-affinity IgE receptor, FcεR1. Preclinical studies have demonstrated a role for SYK in models of allergic inflammation, but a role in airwa...

Alternative Titles

Full title

Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1464495091

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1464495091

Other Identifiers

ISSN

1044-1549

E-ISSN

1535-4989

DOI

10.1165/rcmb.2013-0200OC

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