Metformin trims fats to restore insulin sensitivity
Metformin trims fats to restore insulin sensitivity
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Despite metformin being one of the most commonly prescribed drugs for the treatment of diabetes, how it elicits its therapeutic effects has remained mysterious. A new study in mice shows that inhibitory phosphorylation of acetyl-coA carboxylases Acc1 and Acc2 by the AMP-activated protein kinase (AMPK) is essential for the ability of metformin to im...
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Full title
Metformin trims fats to restore insulin sensitivity
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TN_cdi_proquest_miscellaneous_1465863645
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1465863645
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.3414
