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FLZ Alleviates the Memory Deficits in Transgenic Mouse Model of Alzheimers Disease via Decreasing Be...

FLZ Alleviates the Memory Deficits in Transgenic Mouse Model of Alzheimers Disease via Decreasing Be...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1468358869

FLZ Alleviates the Memory Deficits in Transgenic Mouse Model of Alzheimers Disease via Decreasing Beta-Amyloid Production and Tau Hyperphosphorylation: e78033

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Full title

FLZ Alleviates the Memory Deficits in Transgenic Mouse Model of Alzheimers Disease via Decreasing Beta-Amyloid Production and Tau Hyperphosphorylation: e78033

Journal title

PloS one, 2013-11, Vol.8 (11)

Language

English

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Contents

Alzheimer's disease (AD) is the most common cause of dementia worldwide and mainly characterized by the aggregated beta -amyloid (A beta ) and hyperphosphorylated tau. FLZ is a novel synthetic derivative of natural squamosamide and has been proved to improve memory deficits in dementia animal models. In this study, we aimed to investigate the mecha...

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Full title

FLZ Alleviates the Memory Deficits in Transgenic Mouse Model of Alzheimers Disease via Decreasing Beta-Amyloid Production and Tau Hyperphosphorylation: e78033

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Record Identifier

TN_cdi_proquest_miscellaneous_1468358869

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1468358869

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E-ISSN

1932-6203

DOI

10.1371/journal.pone.0078033

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