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Underactivation of the adiponectin–adiponectin receptor 1 axis in clear cell renal cell carcinoma: i...

Underactivation of the adiponectin–adiponectin receptor 1 axis in clear cell renal cell carcinoma: i...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1492671887

Underactivation of the adiponectin–adiponectin receptor 1 axis in clear cell renal cell carcinoma: implications for progression

About this item

Full title

Underactivation of the adiponectin–adiponectin receptor 1 axis in clear cell renal cell carcinoma: implications for progression

Publisher

Dordrecht: Springer Netherlands

Journal title

Clinical & experimental metastasis, 2014-02, Vol.31 (2), p.169-183

Language

English

Formats

Publication information

Publisher

Dordrecht: Springer Netherlands

More information

Scope and Contents

Contents

Energy-sensing pathways, normally coordinated by 5′ AMP-activated protein kinase (AMPK), are dysregulated in renal cell carcinoma (RCC). Obesity can accentuate the pre-existing pro-tumorigenic metabolic machinery in RCC cells through its associated obesogenic hormonal milieu, characterized by lower circulating levels of adiponectin. In RCC patients...

Alternative Titles

Full title

Underactivation of the adiponectin–adiponectin receptor 1 axis in clear cell renal cell carcinoma: implications for progression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1492671887

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1492671887

Other Identifiers

ISSN

0262-0898

E-ISSN

1573-7276

DOI

10.1007/s10585-013-9618-1

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