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Compensatory and non-compensatory effects on protein expression following BCL-2 suppression by antis...

Compensatory and non-compensatory effects on protein expression following BCL-2 suppression by antis...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1496893475

Compensatory and non-compensatory effects on protein expression following BCL-2 suppression by antisense oligonucleotides

About this item

Full title

Compensatory and non-compensatory effects on protein expression following BCL-2 suppression by antisense oligonucleotides

Publisher

Boston: Springer US

Journal title

Medical oncology (Northwood, London, England), 2012-09, Vol.29 (3), p.2284-2290

Language

English

Formats

Publication information

Publisher

Boston: Springer US

More information

Scope and Contents

Contents

Antisense oligonucleotides (oligos) have been employed against in vivo and in vitro prostate cancer models targeting growth regulatory proteins. In LNCaP cells, we evaluated both monospecific and bispecific oligos that targeted and comparably suppressed the expression of bcl-2, an apoptosis inhibitory protein. Cells compensated with both suppressed...

Alternative Titles

Full title

Compensatory and non-compensatory effects on protein expression following BCL-2 suppression by antisense oligonucleotides

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1496893475

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1496893475

Other Identifiers

ISSN

1357-0560

E-ISSN

1559-131X

DOI

10.1007/s12032-011-0097-4

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