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Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and me...

Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and me...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1496893733

Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1

About this item

Full title

Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2014-01, Vol.33 (4), p.514-524

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Previous studies have demonstrated that microRNA (miRNA) expression is altered in human cancer. However, the molecular mechanism underlying these changes in miRNA expression remains unclear. In this study, we investigated the epigenetic modification of miR-124 genes and the potential function of miR-124 in pancreatic cancer. Using pyrosequencing an...

Alternative Titles

Full title

Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1496893733

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1496893733

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/onc.2012.598

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