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Glucocorticoid‐mediated repression of T‐cell receptor signalling is impaired in glucocorticoid recep...

Glucocorticoid‐mediated repression of T‐cell receptor signalling is impaired in glucocorticoid recep...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1499146489

Glucocorticoid‐mediated repression of T‐cell receptor signalling is impaired in glucocorticoid receptor exon 2‐disrupted mice

About this item

Full title

Glucocorticoid‐mediated repression of T‐cell receptor signalling is impaired in glucocorticoid receptor exon 2‐disrupted mice

Publisher

United States: Nature Publishing Group

Journal title

Immunology and cell biology, 2014-02, Vol.92 (2), p.148-155

Language

English

Formats

Publication information

Publisher

United States: Nature Publishing Group

More information

Scope and Contents

Contents

Studies using glucocorticoid receptor exon 2‐disrupted knockout (GR2KO) mice provided strong evidence against an obligatory role for glucocorticoid receptor (GR) signalling in T‐cell selection. These mice express a truncated form of the GR that is incapable of transmitting a range of glucocorticoid (GC)‐induced signals, including GC‐induced thymocy...

Alternative Titles

Full title

Glucocorticoid‐mediated repression of T‐cell receptor signalling is impaired in glucocorticoid receptor exon 2‐disrupted mice

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1499146489

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1499146489

Other Identifiers

ISSN

0818-9641

E-ISSN

1440-1711

DOI

10.1038/icb.2013.76

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