Sequencing depth and coverage: key considerations in genomic analyses
Sequencing depth and coverage: key considerations in genomic analyses
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
The average depth of sequencing coverage can be defined theoretically as
LN/G
, where
L
is the read length,
N
is the number of reads and
G
is the haploid genome length.
The breadth of coverage is the percentage of target bases that have been sequenced for a given number of times.
Hybrid sequencing approac...
Alternative Titles
Full title
Sequencing depth and coverage: key considerations in genomic analyses
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TN_cdi_proquest_miscellaneous_1500789790
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1500789790
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ISSN
1471-0056
E-ISSN
1471-0064
DOI
10.1038/nrg3642
