Nonagonistic Dectin-1 ligand transforms CpG into a multitask nanoparticulate TLR9 agonist
Nonagonistic Dectin-1 ligand transforms CpG into a multitask nanoparticulate TLR9 agonist
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
CpG DNA, a ligand for Toll-like receptor 9 (TLR9), has been one of the most promising immunotherapeutic agents. Although there are several types of potent humanized CpG oligodeoxynucleotide (ODN), developing “all-in-one” CpG ODNs activating both B cells and plasmacytoid dendritic cells forming a stable nanoparticle without aggregation has not been...
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Full title
Nonagonistic Dectin-1 ligand transforms CpG into a multitask nanoparticulate TLR9 agonist
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TN_cdi_proquest_miscellaneous_1512331494
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1512331494
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1319268111
