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ArticlesPeer ReviewedFull Text
STING agonists activate latently infected cells and enhance SIV-specific responses ex vivo in naturally SIV controlled cynomolgus macaques
Author / Creator:Yamamoto, Takuya ; Kanuma, Tomohiro ; Takahama, Shokichi ; Okamura, Tomotaka ; Moriishi, Eiko ; Ishii, Ken J. ; Terahara, Kazutaka ; Yasutomi, Yasuhiro
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-04, Vol.9 (1), p.5917-5917, Article 5917
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Leucine-rich alpha 2 glycoprotein is a new marker for active disease of tuberculosis
Author / Creator:Fujimoto, Minoru ; Matsumoto, Tomoshige ; Serada, Satoshi ; Tsujimura, Yusuke ; Hashimoto, Shoji ; Yasutomi, Yasuhiro ; Naka, Tetsuji
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-02, Vol.10 (1), p.3384-3384, Article 3384
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ArticlesPeer ReviewedFull Text
Diabetes Mellitus Accelerates Aβ Pathology in Brain Accompanied by Enhanced GAβ Generation in Nonhuman Primates
Author / Creator:Okabayashi, Sachi ; Shimozawa, Nobuhiro ; Yasutomi, Yasuhiro ; Yanagisawa, Katsuhiko ; Kimura, Nobuyuki
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-02, Vol.10 (2), p.e0117362-e0117362
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COVID-19 cynomolgus macaque model reflecting human COVID-19 pathological conditions
Author / Creator:Urano, Emiko ; Okamura, Tomotaka ; Ono, Chikako ; Ueno, Shiori ; Nagata, Satoshi ; Kamada, Haruhiko ; Higuchi, Mahoko ; Furukawa, Mugi ; Kamitani, Wataru ; Matsuura, Yoshiharu ; Kawaoka, Yoshihiro ; Yasutomi, Yasuhiro
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-10, Vol.118 (43), p.1-9
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ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury
Author / Creator:Yamaguchi, Tomokazu ; Hoshizaki, Midori ; Minato, Takafumi ; Nirasawa, Satoru ; Asaka, Masamitsu N. ; Niiyama, Mayumi ; Imai, Masaki ; Uda, Akihiko ; Chan, Jasper Fuk-Woo ; Takahashi, Saori ; An, Jianbo ; Saku, Akari ; Nukiwa, Ryota ; Utsumi, Daichi ; Kiso, Maki ; Yasuhara, Atsuhiro ; Poon, Vincent Kwok-Man ; Chan, Chris Chung-Sing ; Fujino, Yuji ; Motoyama, Satoru ; Nagata, Satoshi ; Penninger, Josef M. ; Kamada, Haruhiko ; Yuen, Kwok-Yung ; Kamitani, Wataru ; Maeda, Ken ; Kawaoka, Yoshihiro ; Yasutomi, Yasuhiro ; Imai, Yumiko ; Kuba, Keiji
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-11, Vol.12 (1), p.6791-13, Article 6791
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Nonagonistic Dectin-1 ligand transforms CpG into a multitask nanoparticulate TLR9 agonist
Author / Creator:Kobiyama, Kouji ; Aoshi, Taiki ; Narita, Hirotaka ; Kuroda, Etsushi ; Hayashi, Masayuki ; Tetsutani, Kohhei ; Koyama, Shohei ; Mochizuki, Shinichi ; Sakurai, Kazuo ; Katakai, Yuko ; Yasutomi, Yasuhiro ; Saijo, Shinobu ; Iwakura, Yoichiro ; Akira, Shizuo ; Coban, Cevayir ; Ishii, Ken J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (8), p.3086-3091
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A New Mouse Model of Chronic Myocarditis Induced by Recombinant Bacille Calmette–Guèrin Expressing a T-Cell Epitope of Cardiac Myosin Heavy Chain-α
Author / Creator:Tajiri, Kazuko ; Imanaka-Yoshida, Kyoko ; Tsujimura, Yusuke ; Matsuo, Kazuhiro ; Hiroe, Michiaki ; Aonuma, Kazutaka ; Ieda, Masaki ; Yasutomi, Yasuhiro
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-01, Vol.22 (2), p.794
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Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques
Author / Creator:Nagatake, Takahiro ; Kishino, Shigenobu ; Urano, Emiko ; Murakami, Haruka ; Kitamura, Nahoko ; Konishi, Kana ; Ohno, Harumi ; Tiwari, Prabha ; Morimoto, Sakiko ; Node, Eri ; Adachi, Jun ; Abe, Yuichi ; Isoyama, Junko ; Sawane, Kento ; Honda, Tetsuya ; Inoue, Asuka ; Uwamizu, Akiharu ; Matsuzaka, Takashi ; Miyamoto, Yoichi ; Hirata, So-ichiro ; Saika, Azusa ; Shibata, Yuki ; Hosomi, Koji ; Matsunaga, Ayu ; Shimano, Hitoshi ; Arita, Makoto ; Aoki, Junken ; Oka, Masahiro ; Matsutani, Akira ; Tomonaga, Takeshi ; Kabashima, Kenji ; Miyachi, Motohiko ; Yasutomi, Yasuhiro ; Ogawa, Jun ; Kunisawa, Jun
Publisher:New York: Nature Publishing Group US
Journal title:Mucosal immunology, 2022-02, Vol.15 (2), p.289-300
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ArticlesPeer ReviewedFull Text
Gene expression dataset for whole cochlea of Macaca fascicularis
Author / Creator:Mutai, Hideki ; Miya, Fuyuki ; Shibata, Hiroaki ; Yasutomi, Yasuhiro ; Tsunoda, Tatsuhiko ; Matsunaga, Tatsuo
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-10, Vol.8 (1), p.15554-9, Article 15554
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ArticlesPeer ReviewedFull Text
Construction of complete Tupaia belangeri transcriptome database by whole-genome and comprehensive RNA sequencing
Author / Creator:Sanada, Takahiro ; Tsukiyama-Kohara, Kyoko ; Shin-I, Tadasu ; Yamamoto, Naoki ; Kayesh, Mohammad Enamul Hoque ; Yamane, Daisuke ; Takano, Jun-ichiro ; Shiogama, Yumiko ; Yasutomi, Yasuhiro ; Ikeo, Kazuho ; Gojobori, Takashi ; Mizokami, Masashi ; Kohara, Michinori
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-08, Vol.9 (1), p.12372-12, Article 12372
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Newsletter articlesFull Text
WIPO PUBLISHES PATENT OF MIE UNIVERSITY, BIOCOMO, NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION, FUKUMURA MASAYUKI, YASUTOMI YASUHIRO, KAWANO MITSUO, NOSAKA TETSUYA, OHTSUKA JUNPEI FOR "METHOD FOR PRODU...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2012
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Effects of Mycobacteria Major Secretion Protein, Ag85B, on Allergic Inflammation in the Lung
Author / Creator:Tsujimura, Yusuke ; Inada, Hiroyasu ; Yoneda, Misao ; Fujita, Tomoyuki ; Matsuo, Kazuhiro ; Yasutomi, Yasuhiro
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-09, Vol.9 (9), p.e106807
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DNA vaccine expressing the non-structural proteins of hepatitis C virus diminishes the expression of HCV proteins in a mouse model
Author / Creator:Wada, Takeshi ; Kohara, Michinori ; Yasutomi, Yasuhiro
Publisher:Kidlington: Elsevier Ltd
Journal title:Vaccine, 2013-12, Vol.31 (50), p.5968-5974
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ArticlesPeer ReviewedFull Text
Long-term protective immunity induced by an adjuvant-containing live-attenuated AIDS virus
Author / Creator:Okamura, Tomotaka ; Shimizu, Yuya ; Asaka, Masamitsu N. ; Kanuma, Tomohiro ; Tsujimura, Yusuke ; Yamamoto, Takuya ; Matsuo, Kazuhiro ; Yasutomi, Yasuhiro
Publisher:London: Nature Publishing Group UK
Journal title:npj vaccines, 2021-10, Vol.6 (1), p.124-124, Article 124
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Partial Deletion of Glycoprotein B5R Enhances Vaccinia Virus Neutralization Escape while Preserving Oncolytic Function
Author / Creator:Nakatake, Motomu ; Kurosaki, Hajime ; Kuwano, Nozomi ; Horita, Kosuke ; Ito, Mai ; Kono, Hiromichi ; Okamura, Tomotaka ; Hasegawa, Kosei ; Yasutomi, Yasuhiro ; Nakamura, Takafumi
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy. Oncolytics, 2019-09, Vol.14, p.159-171
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ArticlesPeer ReviewedFull Text
Recombinant Ag85B vaccine by taking advantage of characteristics of human parainfluenza type 2 virus vector showed Mycobacteria-specific immune responses by intranasal immunization
Author / Creator:Watanabe, Kenta ; Matsubara, Akihiro ; Kawano, Mitsuo ; Mizuno, Satoru ; Okamura, Tomotaka ; Tsujimura, Yusuke ; Inada, Hiroyasu ; Nosaka, Tetsuya ; Matsuo, Kazuhiro ; Yasutomi, Yasuhiro
Publisher:Kidlington: Elsevier Ltd
Journal title:Vaccine, 2014-03, Vol.32 (15), p.1727-1735
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Prime-boost-type PspA3 + 2 mucosal vaccine protects cynomolgus macaques from intratracheal challenge with pneumococci
Author / Creator:Yokota, Chieko ; Fujimoto, Kosuke ; Yamakawa, Natsuko ; Kono, Masamitsu ; Miyaoka, Daichi ; Shimohigoshi, Masaki ; Uematsu, Miho ; Watanabe, Miki ; Kamei, Yukari ; Sugimoto, Akira ; Kawasaki, Natsuko ; Yabuno, Takato ; Okamura, Tomotaka ; Kuroda, Eisuke ; Hamaguchi, Shigeto ; Sato, Shintaro ; Hotomi, Muneki ; Akeda, Yukihiro ; Ishii, Ken J ; Yasutomi, Yasuhiro ; Sunami, Kishiko ; Uematsu, Satoshi
Publisher:England
Journal title:Inflammation and regeneration, 2023-11, Vol.43 (1), p.55-55
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Development and Characterization of a Highly Sensitive NanoLuciferase-Based Immunoprecipitation System for the Detection of Anti-Influenza Virus HA Antibodies
Author / Creator:Honda, Tomoko ; Gomi, Sumiko ; Yamane, Daisuke ; Yasui, Fumihiko ; Yamamoto, Takuya ; Munakata, Tsubasa ; Itoh, Yasushi ; Ogasawara, Kazumasa ; Sanada, Takahiro ; Yamaji, Kenzaburo ; Yasutomi, Yasuhiro ; Tsukiyama-Kohara, Kyoko ; Kohara, Michinori
Publisher:United States: American Society for Microbiology
Journal title:mSphere, 2021-05, Vol.6 (3)
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Intratracheal trimerized nanobody cocktail administration suppresses weight loss and prolongs survival of SARS-CoV-2 infected mice
Author / Creator:Nagata, Kayoko ; Utsumi, Daichi ; Asaka, Masamitsu N. ; Maeda, Ryota ; Shirakawa, Kotaro ; Kazuma, Yasuhiro ; Nomura, Ryosuke ; Horisawa, Yoshihito ; Yanagida, Yohei ; Kawai, Yugo ; Sato, Kei ; Yamaoka, Yutaro ; Miyakawa, Kei ; Ryo, Akihide ; Yasutomi, Yasuhiro ; Imura, Akihiro ; Takaori-Kondo, Akifumi
Publisher:London: Nature Publishing Group UK
Journal title:Communications medicine, 2022-11, Vol.2 (1), p.152-152, Article 152
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In Vivo Safety and Persistence of Endoribonuclease Gene-Transduced CD4+ T Cells in Cynomolgus Macaques for HIV-1 Gene Therapy Model
Author / Creator:Chono, Hideto ; Saito, Naoki ; Tsuda, Hiroshi ; Shibata, Hiroaki ; Ageyama, Naohide ; Terao, Keiji ; Yasutomi, Yasuhiro ; Mineno, Junichi ; Kato, Ikunoshin
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-08, Vol.6 (8), p.e23585-e23585
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STING agonists activate latently infected cells and enhance SIV-specific responses ex vivo in naturally SIV controlled cynomolgus macaques

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Leucine-rich alpha 2 glycoprotein is a new marker for active disease of tuberculosis

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Diabetes Mellitus Accelerates Aβ Pathology in Brain Accompanied by Enhanced GAβ Generation in Nonhuman Primates

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COVID-19 cynomolgus macaque model reflecting human COVID-19 pathological conditions

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ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury

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Nonagonistic Dectin-1 ligand transforms CpG into a multitask nanoparticulate TLR9 agonist

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A New Mouse Model of Chronic Myocarditis Induced by Recombinant Bacille Calmette–Guèrin Expressing a T-Cell Epitope of Cardiac Myosin Heavy Chain-α

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Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques

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Gene expression dataset for whole cochlea of Macaca fascicularis

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Construction of complete Tupaia belangeri transcriptome database by whole-genome and comprehensive RNA sequencing

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WIPO PUBLISHES PATENT OF MIE UNIVERSITY, BIOCOMO, NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION, FUKUMURA MASAYUKI, YASUTOMI YASUHIRO, KAWANO MITSUO, NOSAKA TETSUYA, OHTSUKA JUNPEI FOR "METHOD FOR PRODU...

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Effects of Mycobacteria Major Secretion Protein, Ag85B, on Allergic Inflammation in the Lung

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DNA vaccine expressing the non-structural proteins of hepatitis C virus diminishes the expression of HCV proteins in a mouse model

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Long-term protective immunity induced by an adjuvant-containing live-attenuated AIDS virus

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Partial Deletion of Glycoprotein B5R Enhances Vaccinia Virus Neutralization Escape while Preserving Oncolytic Function

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Recombinant Ag85B vaccine by taking advantage of characteristics of human parainfluenza type 2 virus vector showed Mycobacteria-specific immune responses by intranasal immunization

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Prime-boost-type PspA3 + 2 mucosal vaccine protects cynomolgus macaques from intratracheal challenge with pneumococci

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Development and Characterization of a Highly Sensitive NanoLuciferase-Based Immunoprecipitation System for the Detection of Anti-Influenza Virus HA Antibodies

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Intratracheal trimerized nanobody cocktail administration suppresses weight loss and prolongs survival of SARS-CoV-2 infected mice

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In Vivo Safety and Persistence of Endoribonuclease Gene-Transduced CD4+ T Cells in Cynomolgus Macaques for HIV-1 Gene Therapy Model

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