H-Ras forms dimers on membrane surfaces via a protein—protein interface
H-Ras forms dimers on membrane surfaces via a protein—protein interface
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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The lipid-anchored small GTPase Ras is an important signaling node in mammalian cells. A number of observations suggest that Ras is laterally organized within the cell membrane, and this may play a regulatory role in its activation. Lipid anchors composed of palmitoyl and farnesyl moieties in H-, N-, and K-Ras are widely suspected to be responsible...
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Full title
H-Ras forms dimers on membrane surfaces via a protein—protein interface
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TN_cdi_proquest_miscellaneous_1512333151
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1512333151
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1321155111
