Gq/5-HT₂c receptor signals activate a local GABAergic inhibitory feedback circuit to modulate seroto...
Gq/5-HT₂c receptor signals activate a local GABAergic inhibitory feedback circuit to modulate serotonergic firing and anxiety in mice
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Serotonin 2c receptors (5-HT ₂c-Rs) are drug targets for certain mental disorders, including schizophrenia, depression, and anxiety. 5-HT ₂c-Rs are expressed throughout the brain, making it difficult to link behavioral changes to circuit specific receptor expression. Various 5-HT-Rs, including 5-HT ₂c-Rs, are found in the dorsal raphe nucleus (DRN)...
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Full title
Gq/5-HT₂c receptor signals activate a local GABAergic inhibitory feedback circuit to modulate serotonergic firing and anxiety in mice
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TN_cdi_proquest_miscellaneous_1520344688
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1520344688
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1321576111
