Piperine induces apoptosis of lung cancer A549 cells via p53-dependent mitochondrial signaling pathw...
Piperine induces apoptosis of lung cancer A549 cells via p53-dependent mitochondrial signaling pathway
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Author / Creator
Lin, Yi , Xu, Jianping , Liao, Hehe , Li, Lu and Pan, Lei
Publisher
Dordrecht: Springer Netherlands
Journal title
Language
English
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Publisher
Dordrecht: Springer Netherlands
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Scope and Contents
Contents
The aim of this study was to evaluate the cytotoxic and apoptotic effects of piperine on human lung cancer A549 cells and to explore its mechanisms. Piperine was found to exert the greatest cytotoxic effect against A549 cells in a dose-dependent manner, whereas it showed no effect on WI38 human lung fibroblasts. This cell growth-inhibitory effect m...
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Full title
Piperine induces apoptosis of lung cancer A549 cells via p53-dependent mitochondrial signaling pathway
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Record Identifier
TN_cdi_proquest_miscellaneous_1524413064
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1524413064
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ISSN
1010-4283
E-ISSN
1423-0380
DOI
10.1007/s13277-013-1433-4