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Piperine induces apoptosis of lung cancer A549 cells via p53-dependent mitochondrial signaling pathw...

Piperine induces apoptosis of lung cancer A549 cells via p53-dependent mitochondrial signaling pathw...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1524413064

Piperine induces apoptosis of lung cancer A549 cells via p53-dependent mitochondrial signaling pathway

About this item

Full title

Piperine induces apoptosis of lung cancer A549 cells via p53-dependent mitochondrial signaling pathway

Publisher

Dordrecht: Springer Netherlands

Journal title

Tumor biology, 2014-04, Vol.35 (4), p.3305-3310

Language

English

Formats

Publication information

Publisher

Dordrecht: Springer Netherlands

More information

Scope and Contents

Contents

The aim of this study was to evaluate the cytotoxic and apoptotic effects of piperine on human lung cancer A549 cells and to explore its mechanisms. Piperine was found to exert the greatest cytotoxic effect against A549 cells in a dose-dependent manner, whereas it showed no effect on WI38 human lung fibroblasts. This cell growth-inhibitory effect m...

Alternative Titles

Full title

Piperine induces apoptosis of lung cancer A549 cells via p53-dependent mitochondrial signaling pathway

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1524413064

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1524413064

Other Identifiers

ISSN

1010-4283

E-ISSN

1423-0380

DOI

10.1007/s13277-013-1433-4

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