Pharmacological and genomic profiling identifies NF-κB–targeted treatment strategies for mantle cell...
Pharmacological and genomic profiling identifies NF-κB–targeted treatment strategies for mantle cell lymphoma
About this item
Full title
Author / Creator
Rahal, Rami , Frick, Mareike , Romero, Rodrigo , Korn, Joshua M , Kridel, Robert , Chun Chan, Fong , Meissner, Barbara , Bhang, Hyo-eun , Ruddy, Dave , Kauffmann, Audrey , Farsidjani, Ali , Derti, Adnan , Rakiec, Daniel , Naylor, Tara , Pfister, Estelle , Kovats, Steve , Kim, Sunkyu , Dietze, Kerstin , Dörken, Bernd , Steidl, Christian , Tzankov, Alexandar , Hummel, Michael , Monahan, John , Morrissey, Michael P , Fritsch, Christine , Sellers, William R , Cooke, Vesselina G , Gascoyne, Randy D , Lenz, Georg and Stegmeier, Frank
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
A screen for compounds that may inhibit the growth of hematological malignancies reveals the specific dependence of some mantle cell lymphoma (MCL) cell lines on canonical or alternative NF-κB signaling. As also seen in patients, genetic alterations affecting alternative NF-κB signaling confer insensibility to ibrutinib, a compound that was recentl...
Alternative Titles
Full title
Pharmacological and genomic profiling identifies NF-κB–targeted treatment strategies for mantle cell lymphoma
Authors, Artists and Contributors
Author / Creator
Frick, Mareike
Romero, Rodrigo
Korn, Joshua M
Kridel, Robert
Chun Chan, Fong
Meissner, Barbara
Bhang, Hyo-eun
Ruddy, Dave
Kauffmann, Audrey
Farsidjani, Ali
Derti, Adnan
Rakiec, Daniel
Naylor, Tara
Pfister, Estelle
Kovats, Steve
Kim, Sunkyu
Dietze, Kerstin
Dörken, Bernd
Steidl, Christian
Tzankov, Alexandar
Hummel, Michael
Monahan, John
Morrissey, Michael P
Fritsch, Christine
Sellers, William R
Cooke, Vesselina G
Gascoyne, Randy D
Lenz, Georg
Stegmeier, Frank
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1524419494
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1524419494
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.3435
