POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia
POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia
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Author / Creator
Ramsay, Andrew J , Quesada, Víctor , Foronda, Miguel , Conde, Laura , Martínez-Trillos, Alejandra , Villamor, Neus , Rodríguez, David , Kwarciak, Agnieszka , Garabaya, Cecilia , Gallardo, Mercedes , López-Guerra, Mónica , López-Guillermo, Armando , Puente, Xose S , Blasco, María A , Campo, Elías and López-Otín, Carlos
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Carlos López-Otín and colleagues report recurrent mutations in
POT1
in chronic lymphocytic leukemia. This is the first member of the telomeric shelterin complex reported to be mutated in human cancer.
Chronic lymphocytic leukemia (CLL) is the most frequent leukemia in adults
1
,
2
,
3
. We have analyzed exome sequencing d...
Alternative Titles
Full title
POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_1554948316
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1554948316
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.2584
