Safety and activity of ibrutinib plus rituximab for patients with high-risk chronic lymphocytic leuk...
Safety and activity of ibrutinib plus rituximab for patients with high-risk chronic lymphocytic leukaemia: a single-arm, phase 2 study
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Author / Creator
Burger, Jan A, Dr , Keating, Michael J, Prof , Wierda, William G, Prof , Hartmann, Elena, MD , Hoellenriegel, Julia, MS , Rosin, Nathalie Y, PhD , de Weerdt, Iris, MD , Jeyakumar, Ghayathri, MD , Ferrajoli, Alessandra, MD , Cardenas-Turanzas, Marylou, PhD , Lerner, Susan, MS , Jorgensen, Jeffrey L, MD , Nogueras-González, Graciela M, MS , Zacharian, Gracy, MS , Huang, Xuelin, PhD , Kantarjian, Hagop, Prof , Garg, Naveen, MD , Rosenwald, Andreas, Prof and O'Brien, Susan, Prof
Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Contents
Summary Background Ibrutinib, an orally administered covalent inhibitor of Bruton's tyrosine kinase (BTK), is an effective treatment for relapsed chronic lymphocytic leukaemia (CLL). We investigated the activity and safety of the combination of ibrutinib with the monoclonal antibody rituximab in patients with high-risk CLL. Methods In this single-a...
Alternative Titles
Full title
Safety and activity of ibrutinib plus rituximab for patients with high-risk chronic lymphocytic leukaemia: a single-arm, phase 2 study
Authors, Artists and Contributors
Author / Creator
Keating, Michael J, Prof
Wierda, William G, Prof
Hartmann, Elena, MD
Hoellenriegel, Julia, MS
Rosin, Nathalie Y, PhD
de Weerdt, Iris, MD
Jeyakumar, Ghayathri, MD
Ferrajoli, Alessandra, MD
Cardenas-Turanzas, Marylou, PhD
Lerner, Susan, MS
Jorgensen, Jeffrey L, MD
Nogueras-González, Graciela M, MS
Zacharian, Gracy, MS
Huang, Xuelin, PhD
Kantarjian, Hagop, Prof
Garg, Naveen, MD
Rosenwald, Andreas, Prof
O'Brien, Susan, Prof
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1566841019
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1566841019
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ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(14)70335-3