The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogene...
The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesis
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Author / Creator
Zhao, Huijie , Zhu, Lei , Zhu, Yunlu , Cao, Jingli , Li, Shanshan , Huang, Qiongping , Xu, Tao , Huang, Xiao , Yan, Xiumin and Zhu, Xueliang
Publisher
London: Nature Publishing Group UK
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Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
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Contents
Dense multicilia in higher vertebrates are important for luminal flow and the removal of thick mucus. To generate hundreds of basal bodies for multiciliogenesis, specialized terminally differentiated epithelial cells undergo massive centriole amplification. In proliferating cells, however, centriole duplication occurs only once per cell cycle. How...
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Full title
The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesis
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Record Identifier
TN_cdi_proquest_miscellaneous_1566841279
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1566841279
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb2880
