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Alzheimer disease therapy—moving from amyloid-β to tau

Alzheimer disease therapy—moving from amyloid-β to tau

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1566841950

Alzheimer disease therapy—moving from amyloid-β to tau

About this item

Full title

Alzheimer disease therapy—moving from amyloid-β to tau

Author / Creator

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Neurology, 2013-12, Vol.9 (12), p.677-686

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Notable failures of amyloid-β-targeted therapies in late-stage clinical trials for Alzheimer disease (AD) suggest the need for a reassessment of the amyloid cascade hypothesis of AD pathology. Here, Giacobini and Gold discuss the limitations of focusing on amyloid-β, and suggest a shift towards tau-directed therapy. They outline the rationale for s...

Alternative Titles

Full title

Alzheimer disease therapy—moving from amyloid-β to tau

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1566841950

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1566841950

Other Identifiers

ISSN

1759-4758

E-ISSN

1759-4766

DOI

10.1038/nrneurol.2013.223

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