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Estrogen-related receptor α decreases RHOA stability to induce orientated cell migration

Estrogen-related receptor α decreases RHOA stability to induce orientated cell migration

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1615744924

Estrogen-related receptor α decreases RHOA stability to induce orientated cell migration

About this item

Full title

Estrogen-related receptor α decreases RHOA stability to induce orientated cell migration

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (42), p.15108-15113

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Several physiopathological processes require orientated cellular migration. This phenomenon highly depends on members of the RHO family of GTPases. Both excessive and deficient RHO activity impair directional migration. A tight control is thus exerted on these proteins through the regulation of their activation and of their stability. Here we show...

Alternative Titles

Full title

Estrogen-related receptor α decreases RHOA stability to induce orientated cell migration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1615744924

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1615744924

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1402094111

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