Oncogenic roles of Bmi1 and its therapeutic inhibition by histone deacetylase inhibitor in tongue ca...
Oncogenic roles of Bmi1 and its therapeutic inhibition by histone deacetylase inhibitor in tongue cancer
About this item
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Author / Creator
Li, Zhongwu , Wang, Yanling , Yuan, Chunping , Zhu, Yumin , Qiu, Jing , Zhang, Wei , Qi, Bing , Wu, Heming , Ye, Jinhai , Jiang, Hongbing , Yang, Jianrong and Cheng, Jie
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
The polycomb complex protein Bmi1 (B lymphoma Mo-MLV insertion region 1 homolog) mediates epigenetic transcriptional silencing by modifying chromatin structure and is critical for stem cell homeostasis and tumorigenesis. Bmi1 is frequently overexpressed in human malignancies and therefore has key diagnostic and prognostic significance, and holds po...
Alternative Titles
Full title
Oncogenic roles of Bmi1 and its therapeutic inhibition by histone deacetylase inhibitor in tongue cancer
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Record Identifier
TN_cdi_proquest_miscellaneous_1635028172
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1635028172
Other Identifiers
ISSN
0023-6837
E-ISSN
1530-0307
DOI
10.1038/labinvest.2014.123
