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Microglia and the Development of Spongiform Change in Creutzfeldt-Jakob Disease

Microglia and the Development of Spongiform Change in Creutzfeldt-Jakob Disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_16453649

Microglia and the Development of Spongiform Change in Creutzfeldt-Jakob Disease

About this item

Full title

Microglia and the Development of Spongiform Change in Creutzfeldt-Jakob Disease

Publisher

Hagerstown, MD: American Association of Neuropathologists, Inc

Journal title

Journal of neuropathology and experimental neurology, 1998-03, Vol.57 (3), p.246-256

Language

English

Formats

Publication information

Publisher

Hagerstown, MD: American Association of Neuropathologists, Inc

More information

Scope and Contents

Contents

Recent in vitro experiments suggest that neurotoxicity of the prion protein is dependent on the presence of microglia. We have studied 11 cases of Creutzfeldt-Jakob disease (CJD) using immunocytochemistry in combination with computerized image analysis to clarify the relationship between spongiform change and microglial activation. MHC class II-pos...

Alternative Titles

Full title

Microglia and the Development of Spongiform Change in Creutzfeldt-Jakob Disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_16453649

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_16453649

Other Identifiers

ISSN

0022-3069

E-ISSN

1554-6578

DOI

10.1097/00005072-199803000-00006

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