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Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia

Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1660028383

Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia

About this item

Full title

Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2015-02, Vol.518 (7540), p.552-555

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Somatic
TP53
mutations are highly prevalent in therapy-related acute myeloid leukaemia and myelodysplastic syndrome, which arise as complications of cytotoxic chemotherapy or radiotherapy; although it was believed that these
TP53
mutations are directly induced by cytotoxic therapy, new data indicate that they predate cytotoxic therapy a...

Alternative Titles

Full title

Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1660028383

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1660028383

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature13968

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