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Efficacy of a trans-sialidase-ISCOMATRIX subunit vaccine candidate to protect against experimental C...

Efficacy of a trans-sialidase-ISCOMATRIX subunit vaccine candidate to protect against experimental C...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1660417444

Efficacy of a trans-sialidase-ISCOMATRIX subunit vaccine candidate to protect against experimental Chagas disease

About this item

Full title

Efficacy of a trans-sialidase-ISCOMATRIX subunit vaccine candidate to protect against experimental Chagas disease

Publisher

Netherlands: Elsevier Ltd

Journal title

Vaccine, 2015-03, Vol.33 (10), p.1274-1283

Language

English

Formats

Publication information

Publisher

Netherlands: Elsevier Ltd

More information

Scope and Contents

Contents

Abstract Recombinant protein vaccines are safe but elicit low immunological responses. The new generation of adjuvants is currently reversing this situation. Here, a new antigen–adjuvant combination for protection against experimental Chagas disease was assessed. The antigen used in the formulation was a glycosylated mutant inactive trans-sialidase...

Alternative Titles

Full title

Efficacy of a trans-sialidase-ISCOMATRIX subunit vaccine candidate to protect against experimental Chagas disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1660417444

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1660417444

Other Identifiers

ISSN

0264-410X

E-ISSN

1873-2518

DOI

10.1016/j.vaccine.2015.01.044

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