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Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors RORγt and Ahr that leads to IL-17 production by activated B cells
Author / Creator:Bermejo, Daniela A ; Jackson, Shaun W ; Gorosito-Serran, Melisa ; Acosta-Rodriguez, Eva V ; Amezcua-Vesely, Maria C ; Sather, Blythe D ; Singh, Akhilesh K ; Khim, Socheath ; Mucci, Juan ; Liggitt, Denny ; Campetella, Oscar ; Oukka, Mohamed ; Gruppi, Adriana ; Rawlings, David J
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2013-05, Vol.14 (5), p.514-522
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Nasal immunization with a L. lactis-derived trans-sialidase antigen plus c-di-AMP protects against acute oral T. cruzi infection
Author / Creator:Pacini, Maria Florencia ; González, Florencia Belén ; Dinatale, Brenda ; Bulfoni Balbi, Camila ; Villar, Silvina Raquel ; Farré, Cecilia ; Lupi, Giuliana ; Espariz, Martín ; Blancato, Víctor Sebastián ; Magni, Christian ; Marcipar, Iván ; Pérez, Ana Rosa
Publisher:Netherlands: Elsevier Ltd
Journal title:Vaccine, 2022-04, Vol.40 (15), p.2311-2323
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CD8+ T-Cell Responses to Trypanosoma cruzi Are Highly Focused on Strain-Variant trans-Sialidase Epitopes
Author / Creator:Martin, Diana L ; Weatherly, D. Brent ; Laucella, Susana A ; Cabinian, Melissa A ; Crim, Matthew T ; Sullivan, Susan ; Heiges, Mark ; Craven, Sarah H ; Rosenberg, Charles S ; Collins, Matthew H ; Sette, Alessandro ; Postan, Miriam ; Tarleton, Rick L
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2006-08, Vol.2 (8), p.e77-e77
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Cooperativity of catalytic and lectin-like domain of Trypanosoma congolense trans-sialidase modulates its catalytic activity
Author / Creator:Waespy, Mario ; Gbem, Thaddeus Termulun ; Dinesh Kumar, Nilima ; Solaiyappan Mani, Shanmugam ; Rosenau, Jana ; Dietz, Frank ; Kelm, Sørge
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2022-02, Vol.16 (2), p.e0009585
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Identification of Potential Trypanosoma cruzi Trans-Sialidase Inhibitors by Computational Drug Repositioning Approaches
Author / Creator:Uc-Chuc, Miguel A. ; Cigarroa-Toledo, Nohemi ; Acosta-Viana, Karla Y. ; Chan-Pérez, José I. ; Pineda-Cortes, Juan C. ; Villanueva-Alonzo, Hernán de J.
Publisher:Basel: MDPI AG
Journal title:Scientia pharmaceutica, 2024-09, Vol.92 (3), p.40
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Anomeric 1,2,3-triazole-linked sialic acid derivatives show selective inhibition towards a bacterial neuraminidase over a trypanosome trans -sialidase
Author / Creator:de Andrade, Peterson ; Ahmadipour, Sanaz ; Field, Robert A
Publisher:Germany: Beilstein-Institut zur Föerderung der Chemischen Wissenschaften
Journal title:Beilstein journal of organic chemistry, 2022, Vol.18 (1), p.208-216
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Efficacy of a trans-sialidase-ISCOMATRIX subunit vaccine candidate to protect against experimental Chagas disease
Author / Creator:Bontempi, Iván Alejandro ; Vicco, Miguel Hernán ; Cabrera, Gabriel ; Villar, Silvina Raquel ; González, Florencia Belén ; Roggero, Eduardo Angel ; Ameloot, Paul ; Callewaert, Nico ; Pérez, Ana Rosa ; Marcipar, Iván Sergio
Publisher:Netherlands: Elsevier Ltd
Journal title:Vaccine, 2015-03, Vol.33 (10), p.1274-1283
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ASP-2/Trans-sialidase chimeric protein induces robust protective immunity in experimental models of Chagas’ disease
Author / Creator:Castro, Julia T. ; Brito, Rory ; Hojo-Souza, Natalia S. ; Azevedo, Bárbara ; Salazar, Natalia ; Ferreira, Camila P. ; Junqueira, Caroline ; Fernandes, Ana Paula ; Vasconcellos, Ronnie ; Cardoso, Jamille M. ; Aguiar-Soares, Rodrigo D. O. ; Vieira, Paula M. A. ; Carneiro, Cláudia M. ; Valiate, Bruno ; Toledo, Cristiane ; Salazar, Andres M. ; Caballero, Otávia ; Lannes-Vieira, Joseli ; Teixeira, Santuza R. ; Reis, Alexandre B. ; Gazzinelli, Ricardo T.
Publisher:London: Nature Publishing Group UK
Journal title:npj vaccines, 2023-05, Vol.8 (1), p.81-81, Article 81
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ArticlesPeer ReviewedFull Text
Design of Trypanosoma rangeli sialidase mutants with improved trans-sialidase activity
Author / Creator:Nyffenegger, Christian ; Nordvang, Rune Thorbjørn ; Jers, Carsten ; Meyer, Anne S. ; Mikkelsen, Jørn Dalgaard
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-02, Vol.12 (2), p.e0171585-e0171585
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ArticlesPeer ReviewedFull Text
Multivalent sialylation of β-thio-glycoclusters by Trypanosoma cruzi trans sialidase and analysis by high performance anion exchange chromatography
Author / Creator:Agustí, Rosalía ; Cano, María Emilia ; Cagnoni, Alejandro J. ; Kovensky, José ; de Lederkremer, Rosa M. ; Uhrig, María Laura
Publisher:New York: Springer US
Journal title:Glycoconjugate journal, 2016-10, Vol.33 (5), p.809-818
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Benzoic Acid Derivatives with Trypanocidal Activity: Enzymatic Analysis and Molecular Docking Studies toward Trans-Sialidase
Author / Creator:Kashif, Muhammad ; Moreno-Herrera, Antonio ; Villalobos-Rocha, Juan ; Nogueda-Torres, Benjamín ; Pérez-Villanueva, Jaime ; Rodríguez-Villar, Karen ; Medina-Franco, José ; De Andrade, Peterson ; Carvalho, Ivone ; Rivera, Gildardo
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2017-10, Vol.22 (11), p.1863
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ArticlesPeer ReviewedFull Text
Carbohydrate Recognition Specificity of Trans-sialidase Lectin Domain from Trypanosoma congolense
Author / Creator:Waespy, Mario ; Gbem, Thaddeus T. ; Elenschneider, Leroy ; Jeck, André-Philippe ; Day, Christopher J. ; Hartley-Tassell, Lauren ; Bovin, Nicolai ; Tiralongo, Joe ; Haselhorst, Thomas ; Kelm, Sørge
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2015-10, Vol.9 (10), p.e0004120-e0004120
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Comparison of the Protective Effects of Individual Components of Particulated trans-Sialidase (PTCTS), PTC and TS, against High Cholesterol Diet-Induced Atherosclerosis in Rabbits
Author / Creator:Agouni, Abdelali ; Wadt, Nilsa S. Y. ; Ikegami, Renata N. ; Kawakami, Joyce T. ; Reis, Marcia M. ; Pereira, Jaqueline J. ; Higuchi, Maria de Lourdes ; Garavelo, Shérrira M. ; Palomino, Suely A. P.
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:BioMed research international, 2017-01, Vol.2017 (2017), p.1-12
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ArticlesPeer ReviewedFull Text
Intranasal Trans-Sialidase Vaccine Mitigates Acute and Chronic Pathology in a Preclinical Oral Chagas Disease Model
Author / Creator:Pacini, Maria Florencia ; Bulfoni Balbi, Camila ; Dinatale, Brenda ; Farré, Cecilia ; Cacik, Paula ; Gonzalez, Florencia Belén ; Marcipar, Iván ; Pérez, Ana Rosa
Publisher:Switzerland: MDPI AG
Journal title:Vaccines (Basel), 2024-10, Vol.12 (10), p.1171
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Differential Distribution of Genes Encoding the Virulence Factor Trans-Sialidase along Trypanosoma cruzi Discrete Typing Units
Author / Creator:Burgos, Juan M. ; Risso, Marikena G. ; Brenière, Simone Frédérique ; Barnabé, Christian ; Campetella, Oscar ; Leguizamón, María Susana
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-03, Vol.8 (3), p.e58967-e58967
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Rational Design of a New Trypanosoma rangeli Trans-Sialidase for Efficient Sialylation of Glycans
Author / Creator:Jers, Carsten ; Michalak, Malwina ; Larsen, Dorte M. ; Kepp, Kasper P. ; Li, Haiying ; Guo, Yao ; Kirpekar, Finn ; Meyer, Anne S. ; Mikkelsen, Jørn D.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-01, Vol.9 (1), p.e83902-e83902
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Genomic Analyses, Gene Expression and Antigenic Profile of the Trans-Sialidase Superfamily of Trypanosoma cruzi Reveal an Undetected Level of Complexity
Author / Creator:Freitas, Leandro M. ; dos Santos, Sara Lopes ; Rodrigues-Luiz, Gabriela F. ; Mendes, Tiago A. O. ; Rodrigues, Thiago S. ; Gazzinelli, Ricardo T. ; Teixeira, Santuza M. R. ; Fujiwara, Ricardo T. ; Bartholomeu, Daniella C.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-10, Vol.6 (10), p.e25914-e25914
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Differential Expression of a Virulence Factor,the trans-Sialidase, by the Main Trypanosoma cruzi Phylogenetic Lineages
Author / Creator:Risso, Marikena G. ; Garbarino, Gloria B. ; Mocetti, Esteban ; Campetella, Oscar ; Gonzlez Cappa, Stella M. ; Buscaglia, Carlos A. ; Leguizamn, Susana M.
Publisher:Chicago, IL: The University of Chicago Press
Journal title:The Journal of infectious diseases, 2004-06, Vol.189 (12), p.2250-2259
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Stage-specific expression of Trypanosoma cruzi trans-sialidase involves highly conserved 3' untranslated regions
Author / Creator:Jäger, Adriana V ; Muiá, Romina P ; Campetella, Oscar
Publisher:Oxford, UK: Oxford, UK : Blackwell Publishing Ltd
Journal title:FEMS microbiology letters, 2008-06, Vol.283 (2), p.182-188
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Trypanosoma cruzi Binds to Cytokeratin through Conserved Peptide Motifs Found in the Laminin-G-Like Domain of the gp85/Trans-sialidase Proteins
Author / Creator:Teixeira, Andre Azevedo Reis ; de Vasconcelos, Veronica de Cássia Sardinha ; Colli, Walter ; Alves, Maria Júlia Manso ; Giordano, Ricardo José
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2015-09, Vol.9 (9), p.e0004099-e0004099
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Showing 1 to 20 of 310 results

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Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors RORγt and Ahr that leads to IL-17 production by activated B cells

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Nasal immunization with a L. lactis-derived trans-sialidase antigen plus c-di-AMP protects against acute oral T. cruzi infection

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CD8+ T-Cell Responses to Trypanosoma cruzi Are Highly Focused on Strain-Variant trans-Sialidase Epitopes

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Cooperativity of catalytic and lectin-like domain of Trypanosoma congolense trans-sialidase modulates its catalytic activity

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Identification of Potential Trypanosoma cruzi Trans-Sialidase Inhibitors by Computational Drug Repositioning Approaches

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Anomeric 1,2,3-triazole-linked sialic acid derivatives show selective inhibition towards a bacterial neuraminidase over a trypanosome trans -sialidase

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Efficacy of a trans-sialidase-ISCOMATRIX subunit vaccine candidate to protect against experimental Chagas disease

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ASP-2/Trans-sialidase chimeric protein induces robust protective immunity in experimental models of Chagas’ disease

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Design of Trypanosoma rangeli sialidase mutants with improved trans-sialidase activity

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Multivalent sialylation of β-thio-glycoclusters by Trypanosoma cruzi trans sialidase and analysis by high performance anion exchange chromatography

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Benzoic Acid Derivatives with Trypanocidal Activity: Enzymatic Analysis and Molecular Docking Studies toward Trans-Sialidase

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Carbohydrate Recognition Specificity of Trans-sialidase Lectin Domain from Trypanosoma congolense

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Comparison of the Protective Effects of Individual Components of Particulated trans-Sialidase (PTCTS), PTC and TS, against High Cholesterol Diet-Induced Atherosclerosis in Rabbits

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Intranasal Trans-Sialidase Vaccine Mitigates Acute and Chronic Pathology in a Preclinical Oral Chagas Disease Model

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Differential Distribution of Genes Encoding the Virulence Factor Trans-Sialidase along Trypanosoma cruzi Discrete Typing Units

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Rational Design of a New Trypanosoma rangeli Trans-Sialidase for Efficient Sialylation of Glycans

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Genomic Analyses, Gene Expression and Antigenic Profile of the Trans-Sialidase Superfamily of Trypanosoma cruzi Reveal an Undetected Level of Complexity

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Differential Expression of a Virulence Factor,the trans-Sialidase, by the Main Trypanosoma cruzi Phylogenetic Lineages

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Stage-specific expression of Trypanosoma cruzi trans-sialidase involves highly conserved 3' untranslated regions

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Trypanosoma cruzi Binds to Cytokeratin through Conserved Peptide Motifs Found in the Laminin-G-Like Domain of the gp85/Trans-sialidase Proteins

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