Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing a...
Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage
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New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Type 2 immune responses are often associated with the expression of chitinase-like Ym proteins, but their role is unclear. Allen and colleagues show that Ym1 and Ym2 act on γδ T cells to increase their expression of IL-17A and enhance the recruitment of neutrophils.
Enzymatically inactive chitinase-like proteins (CLPs) such as BRP-39, Ym1 and Ym...
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Full title
Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage
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TN_cdi_proquest_miscellaneous_1664194268
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1664194268
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.3023
