The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation
About this item
Full title
Author / Creator
Franklin, Bernardo S , Bossaller, Lukas , De Nardo, Dominic , Ratter, Jacqueline M , Stutz, Andrea , Engels, Gudrun , Brenker, Christoph , Nordhoff, Mark , Mirandola, Sandra R , Al-Amoudi, Ashraf , Mangan, Matthew S , Zimmer, Sebastian , Monks, Brian G , Fricke, Martin , Schmidt, Reinhold E , Espevik, Terje , Jones, Bernadette , Jarnicki, Andrew G , Hansbro, Philip M , Busto, Patricia , Marshak-Rothstein, Ann , Hornemann, Simone , Aguzzi, Adriano , Kastenmüller, Wolfgang and Latz, Eicke
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Various endogenous and pathogen-derived stimuli trigger the assembly of cytosolic multimolecular 'speck' platforms coordinated by the adapter ASC. Latz and colleagues demonstrate that ASC specks have extracellular functions that can prolong inflammation.
Microbes or danger signals trigger inflammasome sensors, which induce polymerization of the...
Alternative Titles
Full title
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation
Authors, Artists and Contributors
Author / Creator
Bossaller, Lukas
De Nardo, Dominic
Ratter, Jacqueline M
Stutz, Andrea
Engels, Gudrun
Brenker, Christoph
Nordhoff, Mark
Mirandola, Sandra R
Al-Amoudi, Ashraf
Mangan, Matthew S
Zimmer, Sebastian
Monks, Brian G
Fricke, Martin
Schmidt, Reinhold E
Espevik, Terje
Jones, Bernadette
Jarnicki, Andrew G
Hansbro, Philip M
Busto, Patricia
Marshak-Rothstein, Ann
Hornemann, Simone
Aguzzi, Adriano
Kastenmüller, Wolfgang
Latz, Eicke
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1664206378
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1664206378
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2913
