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Associations between functional polymorphisms in the NFκB signaling pathway and response to anti-TNF...

Associations between functional polymorphisms in the NFκB signaling pathway and response to anti-TNF...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1664206587

Associations between functional polymorphisms in the NFκB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease

About this item

Full title

Associations between functional polymorphisms in the NFκB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease

Publisher

London: Nature Publishing Group UK

Journal title

The pharmacogenomics journal, 2014-12, Vol.14 (6), p.526-534

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Antitumor necrosis factor-α (TNF-α) is used for treatment of severe cases of inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC). However, one-third of the patients do not respond to the treatment. Genetic markers may predict individual response to anti-TNF therapy. Using a candidate gene approach, 39 mainl...

Alternative Titles

Full title

Associations between functional polymorphisms in the NFκB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1664206587

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1664206587

Other Identifiers

ISSN

1470-269X

E-ISSN

1473-1150

DOI

10.1038/tpj.2014.19

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