Suppressor of Deltex mediates Pez degradation and modulates Drosophila midgut homeostasis
Suppressor of Deltex mediates Pez degradation and modulates Drosophila midgut homeostasis
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Author / Creator
Wang, Chao , Zhang, Wenxiang , Yin, Meng-Xin , Hu, Lianxin , Li, Peixue , Xu, Jiajun , Huang, Hongling , Wang, Shimin , Lu, Yi , Wu, Wenqing , Ho, Margaret S. , Li, Lin , Zhao, Yun and Zhang, Lei
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Pez functions as an upstream negative regulator of Yorkie (Yki) to regulate intestinal stem cell (ISC) proliferation and is essential for the activity of the Hippo pathway specifically in the
Drosophila
midgut epithelium. Here we report that Suppressor of Deltex (Su(dx)) acts as a negative regulator of Pez. We show that Su(dx) targets Pez for...
Alternative Titles
Full title
Suppressor of Deltex mediates Pez degradation and modulates Drosophila midgut homeostasis
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Record Identifier
TN_cdi_proquest_miscellaneous_1667348592
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1667348592
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms7607
