Polycomb Protein EED is Required for Silencing of Pluripotency Genes upon ESC Differentiation
Polycomb Protein EED is Required for Silencing of Pluripotency Genes upon ESC Differentiation
About this item
Full title
Author / Creator
Publisher
Boston: Springer US
Journal title
Language
English
Formats
Publication information
Publisher
Boston: Springer US
Subjects
More information
Scope and Contents
Contents
Eed (embryonic ectoderm development) is a core component of the Polycomb Repressive Complex 2 (PRC2) which catalyzes the methylation of histone H3 lysine 27 (H3K27). Trimethylated H3K27 (H3K27me3) can act as a signal for PRC1 recruitment in the process of gene silencing and chromatin condensation. Previous studies with Eed KO ESCs revealed a failur...
Alternative Titles
Full title
Polycomb Protein EED is Required for Silencing of Pluripotency Genes upon ESC Differentiation
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1668251055
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1668251055
Other Identifiers
ISSN
1550-8943,2629-3269
E-ISSN
1558-6804,2629-3277
DOI
10.1007/s12015-014-9550-z
