Reversing excitatory GABAAR signaling restores synaptic plasticity and memory in a mouse model of Do...
Reversing excitatory GABAAR signaling restores synaptic plasticity and memory in a mouse model of Down syndrome
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Both chronic and acute treatment of adult Ts65Dn mice with the FDA-approved NKCC1 inhibitor bumetanide suppressed aberrant excitatory GABA
A
R signaling and rescued synaptic plasticity deficits and cognitive disabilities in this mouse model of Down syndrome.
Down syndrome (DS) is the most frequent genetic cause of intellectual disability,...
Alternative Titles
Full title
Reversing excitatory GABAAR signaling restores synaptic plasticity and memory in a mouse model of Down syndrome
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1672093614
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1672093614
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.3827
