The C9orf72 repeat expansion itself is methylated in ALS and FTLD patients
The C9orf72 repeat expansion itself is methylated in ALS and FTLD patients
About this item
Full title
Author / Creator
Xi, Zhengrui , Zhang, Ming , Bruni, Amalia C. , Maletta, Raffaele G. , Colao, Rosanna , Fratta, Pietro , Polke, James M. , Sweeney, Mary G. , Mudanohwo, Ese , Nacmias, Benedetta , Sorbi, Sandro , Tartaglia, Maria Carmela , Rainero, Innocenzo , Rubino, Elisa , Pinessi, Lorenzo , Galimberti, Daniela , Surace, Ezequiel I. , McGoldrick, Philip , McKeever, Paul , Moreno, Danielle , Sato, Christine , Liang, Yan , Keith, Julia , Zinman, Lorne , Robertson, Janice and Rogaeva, Ekaterina
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
The most common cause of both amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) is a G
4
C
2
-repeat expansion in
C9orf72.
However, the lower limit for pathological repeats has not been established and expansions with different sizes could have different pathological consequences. One of the implicat...
Alternative Titles
Full title
The C9orf72 repeat expansion itself is methylated in ALS and FTLD patients
Authors, Artists and Contributors
Author / Creator
Zhang, Ming
Bruni, Amalia C.
Maletta, Raffaele G.
Colao, Rosanna
Fratta, Pietro
Polke, James M.
Sweeney, Mary G.
Mudanohwo, Ese
Nacmias, Benedetta
Sorbi, Sandro
Tartaglia, Maria Carmela
Rainero, Innocenzo
Rubino, Elisa
Pinessi, Lorenzo
Galimberti, Daniela
Surace, Ezequiel I.
McGoldrick, Philip
McKeever, Paul
Moreno, Danielle
Sato, Christine
Liang, Yan
Keith, Julia
Zinman, Lorne
Robertson, Janice
Rogaeva, Ekaterina
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1680449874
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1680449874
Other Identifiers
ISSN
0001-6322
E-ISSN
1432-0533
DOI
10.1007/s00401-015-1401-8
