Pembrolizumab for the Treatment of Non–Small-Cell Lung Cancer
Pembrolizumab for the Treatment of Non–Small-Cell Lung Cancer
About this item
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Author / Creator
KEYNOTE-001 Investigators , Garon, Edward B , Rizvi, Naiyer A , Hui, Rina , Leighl, Natasha , Balmanoukian, Ani S , Eder, Joseph Paul , Patnaik, Amita , Aggarwal, Charu , Gubens, Matthew , Horn, Leora , Carcereny, Enric , Ahn, Myung-Ju , Felip, Enriqueta , Lee, Jong-Seok , Hellmann, Matthew D , Hamid, Omid , Goldman, Jonathan W , Soria, Jean-Charles , Dolled-Filhart, Marisa , Rutledge, Ruth Z , Zhang, Jin , Lunceford, Jared K , Rangwala, Reshma , Lubiniecki, Gregory M , Roach, Charlotte , Emancipator, Kenneth and Gandhi, Leena
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Pembrolizumab, an inhibitor of programmed cell death 1 (PD-1), produced responses in 24% of patients with non–small-cell lung cancer, with a median overall survival of 16.2 months. The response rate increased to 45% if more than 50% of tumor cells expressed the PD-1 ligand.
Lung cancer is the leading cause of cancer-related death worldwide.
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Alternative Titles
Full title
Pembrolizumab for the Treatment of Non–Small-Cell Lung Cancer
Authors, Artists and Contributors
Author / Creator
Garon, Edward B
Rizvi, Naiyer A
Hui, Rina
Leighl, Natasha
Balmanoukian, Ani S
Eder, Joseph Paul
Patnaik, Amita
Aggarwal, Charu
Gubens, Matthew
Horn, Leora
Carcereny, Enric
Ahn, Myung-Ju
Felip, Enriqueta
Lee, Jong-Seok
Hellmann, Matthew D
Hamid, Omid
Goldman, Jonathan W
Soria, Jean-Charles
Dolled-Filhart, Marisa
Rutledge, Ruth Z
Zhang, Jin
Lunceford, Jared K
Rangwala, Reshma
Lubiniecki, Gregory M
Roach, Charlotte
Emancipator, Kenneth
Gandhi, Leena
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1682891456
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1682891456
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1501824