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Impacts of PICALM and CLU variants associated with Alzheimer’s disease on the functional connectivit...

Impacts of PICALM and CLU variants associated with Alzheimer’s disease on the functional connectivit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1683348083

Impacts of PICALM and CLU variants associated with Alzheimer’s disease on the functional connectivity of the hippocampus in healthy young adults

About this item

Full title

Impacts of PICALM and CLU variants associated with Alzheimer’s disease on the functional connectivity of the hippocampus in healthy young adults

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Brain Structure and Function, 2015-05, Vol.220 (3), p.1463-1475

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

PICALM rs3851179 and CLU rs11136000 have been recently associated with Alzheimer’s disease (AD). Investigating the effects of these genetic variants on the resting-state functional connectivity (rsFC) of the hippocampus may provide new insight into AD pathogenesis. We investigated the main effects and interactions of these two genetic variants on h...

Alternative Titles

Full title

Impacts of PICALM and CLU variants associated with Alzheimer’s disease on the functional connectivity of the hippocampus in healthy young adults

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1683348083

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1683348083

Other Identifiers

ISSN

1863-2653

E-ISSN

1863-2661,0340-2061

DOI

10.1007/s00429-014-0738-4

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