KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque...
KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
A high percentage of smooth muscle cells in atherosclerotic lesions lose expression of smooth muscle marker proteins and acquire the phenotype of other cell types, a process of functional importance in lesion pathogenesis that is controlled by the transcription factor KLF4.
Previous studies investigating the role of smooth muscle cells (SMCs) an...
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Full title
KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis
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TN_cdi_proquest_miscellaneous_1686415745
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1686415745
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.3866
