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Thrombin-dependent intravascular leukocyte trafficking regulated by fibrin and the platelet receptor...

Thrombin-dependent intravascular leukocyte trafficking regulated by fibrin and the platelet receptor...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1699489218

Thrombin-dependent intravascular leukocyte trafficking regulated by fibrin and the platelet receptors GPIb and PAR4

About this item

Full title

Thrombin-dependent intravascular leukocyte trafficking regulated by fibrin and the platelet receptors GPIb and PAR4

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2015-07, Vol.6 (1), p.7835-7835, Article 7835

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Thrombin is a central regulator of leukocyte recruitment and inflammation at sites of vascular injury, a function thought to involve primarily endothelial PAR cleavage. Here we demonstrate the existence of a distinct leukocyte-trafficking mechanism regulated by components of the haemostatic system, including platelet PAR4, GPIbα and fibrin. Utilizi...

Alternative Titles

Full title

Thrombin-dependent intravascular leukocyte trafficking regulated by fibrin and the platelet receptors GPIb and PAR4

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1699489218

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1699489218

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms8835

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