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Involvement of Organic Cation Transporters in the Clearance and Milk Secretion of Thiamine in Mice

Involvement of Organic Cation Transporters in the Clearance and Milk Secretion of Thiamine in Mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1701486979

Involvement of Organic Cation Transporters in the Clearance and Milk Secretion of Thiamine in Mice

About this item

Full title

Involvement of Organic Cation Transporters in the Clearance and Milk Secretion of Thiamine in Mice

Publisher

New York: Springer US

Journal title

Pharmaceutical research, 2015-07, Vol.32 (7), p.2192-2204

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Purpose
To investigate the role of organic cation transporters (Octs) and multidrug and toxin extrusion protein 1 (Mate1) in the disposition of thiamine.
Methods
The uptake of [
3
H]thiamine was determined in Oct1-, Oct2-, and Oct3-expressing HEK293 cells and freshly isolated hepatocytes. A pharmacokinetic study of thiamine-
d
...

Alternative Titles

Full title

Involvement of Organic Cation Transporters in the Clearance and Milk Secretion of Thiamine in Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1701486979

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1701486979

Other Identifiers

ISSN

0724-8741,1573-904X

E-ISSN

1573-904X

DOI

10.1007/s11095-014-1608-8

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