Inhibition of carbonic anhydrase IX (CA9) sensitizes renal cell carcinoma to ionizing radiation
Inhibition of carbonic anhydrase IX (CA9) sensitizes renal cell carcinoma to ionizing radiation
About this item
Full title
Author / Creator
Publisher
Greece: D.A. Spandidos
Journal title
Language
English
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Publication information
Publisher
Greece: D.A. Spandidos
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More information
Scope and Contents
Contents
While normal kidneys are relatively sensitive to ionizing radiation (IR), renal cell carcinoma (RCC) is considered radioresistant. Carbonic anhydrase IX (CA9), an enzyme that maintains intracellular pH by carbon dioxide dissolution, is upregulated in the majority of RCC, but not in normal kidneys. Since regulation of intracellular pH may enhance ra...
Alternative Titles
Full title
Inhibition of carbonic anhydrase IX (CA9) sensitizes renal cell carcinoma to ionizing radiation
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Record Identifier
TN_cdi_proquest_miscellaneous_1706578158
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1706578158
Other Identifiers
ISSN
1021-335X
E-ISSN
1791-2431
DOI
10.3892/or.2015.4184
