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Neuroprotection induced by the adenosine A sub(2A) antagonist CSC in the 6-OHDA rat model of parkins...

Neuroprotection induced by the adenosine A sub(2A) antagonist CSC in the 6-OHDA rat model of parkins...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17191096

Neuroprotection induced by the adenosine A sub(2A) antagonist CSC in the 6-OHDA rat model of parkinsonism: effect on the activity of striatal output pathways

About this item

Full title

Neuroprotection induced by the adenosine A sub(2A) antagonist CSC in the 6-OHDA rat model of parkinsonism: effect on the activity of striatal output pathways

Journal title

Experimental brain research, 2005-09, Vol.165 (3), p.362-374

Language

English

Formats

More information

Scope and Contents

Contents

In Parkinson's disease (PD), the striatal dopamine depletion and the following overactivation of the indirect pathway of the basal ganglia leads to very early disinhibition of the subthalamic nucleus (STN) that may contribute to the progression of PD by glutamatergic overstimulation of the dopaminergic neurons in the substantia nigra. Adenosine A s...

Alternative Titles

Full title

Neuroprotection induced by the adenosine A sub(2A) antagonist CSC in the 6-OHDA rat model of parkinsonism: effect on the activity of striatal output pathways

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_17191096

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17191096

Other Identifiers

ISSN

0014-4819

E-ISSN

1432-1106

DOI

10.1007/s00221-005-2302-1

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