Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The X-ray crystal structure of the human glycine receptor in the presence of strychnine, an antagonist, reveals how antagonist binding leads to closure of the channel pore.
Structure of human GlyR
The strychnine-sensitive glycine receptor (GlyR) mediates neurotransmission throughout the spinal cord and brainstem. These ligand-gated channels c...
Alternative Titles
Full title
Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1721349205
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1721349205
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature14972
