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Engineered CHO cells for production of diverse, homogeneous glycoproteins

Engineered CHO cells for production of diverse, homogeneous glycoproteins

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1722180737

Engineered CHO cells for production of diverse, homogeneous glycoproteins

About this item

Full title

Engineered CHO cells for production of diverse, homogeneous glycoproteins

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2015-08, Vol.33 (8), p.842-844

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

A knockout study of all human glycosyltransferases encoded in CHO cells provides a guide to producing proteins with desired glycosylation patterns.
Production of glycoprotein therapeutics in Chinese hamster ovary (CHO) cells is limited by the cells' generic capacity for
N-
glycosylation, and production of glycoproteins with desirable homog...

Alternative Titles

Full title

Engineered CHO cells for production of diverse, homogeneous glycoproteins

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1722180737

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1722180737

Other Identifiers

ISSN

1087-0156

E-ISSN

1546-1696

DOI

10.1038/nbt.3280

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