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Dual effect of pyruvate in isolated nerve terminals: generation of reactive oxygen species and prote...

Dual effect of pyruvate in isolated nerve terminals: generation of reactive oxygen species and prote...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17228298

Dual effect of pyruvate in isolated nerve terminals: generation of reactive oxygen species and protection of aconitase

About this item

Full title

Dual effect of pyruvate in isolated nerve terminals: generation of reactive oxygen species and protection of aconitase

Publisher

United States: Springer Nature B.V

Journal title

Neurochemical research, 2005-10, Vol.30 (10), p.1331-1338

Language

English

Formats

Publication information

Publisher

United States: Springer Nature B.V

More information

Scope and Contents

Contents

Generation of reactive oxygen species (ROS) in synaptosomes was investigated in the presence of different substrates. When pyruvate was used as a substrate an increased rate of hydrogen peroxide formation was detected by the Amplex Red fluorescent assay, but aconitase, which is known to be a highly sensitive enzyme to ROS was not inhibited. In cont...

Alternative Titles

Full title

Dual effect of pyruvate in isolated nerve terminals: generation of reactive oxygen species and protection of aconitase

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_17228298

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17228298

Other Identifiers

ISSN

0364-3190

E-ISSN

1573-6903

DOI

10.1007/s11064-005-8805-0

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