Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway
Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway
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Basingstoke: Nature Publishing
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Language
English
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Publisher
Basingstoke: Nature Publishing
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In response to DNA damage and replication blocks, cells activate pathways that arrest the cell cycle and induce the transcription of genes that facilitate repair. In mammals, ATM (ataxia telangiectasia mutated) kinase together with other checkpoint kinases are important components in this response. We have cloned the rat and human homologs of Sacch...
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Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway
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TN_cdi_proquest_miscellaneous_17306126
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17306126
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1202925
