Safety and efficacy of desmoteplase given 3–9 h after ischaemic stroke in patients with occlusion or...
Safety and efficacy of desmoteplase given 3–9 h after ischaemic stroke in patients with occlusion or high-grade stenosis in major cerebral arteries (DIAS-3): a double-blind, randomised, placebo-controlled phase 3 trial
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Author / Creator
DIAS-3 Investigators , Albers, Gregory W, Prof , von Kummer, Rüdiger, Prof , Truelsen, Thomas, MD , Jensen, Jens-Kristian S, MSc , Ravn, Gabriela M, MSc , Grønning, Bjørn A, MD , Chabriat, Hugues, Prof , Chang, Ku-Chou, MD , Davalos, Antonio E, Prof , Ford, Gary A, Prof , Grotta, James, MD , Kaste, Markku, Prof , Schwamm, Lee H, Prof and Shuaib, Ashfaq, Prof
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
Summary Background Current treatment of ischaemic stroke with thrombolytic therapy is restricted to 3–4·5 h after symptom onset. We aimed to assess the safety and efficacy of desmoteplase, a fibrin-dependent plasminogen activator, given between 3 h and 9 h after symptom onset in patients with occlusion or high-grade stenosis in major cerebral arter...
Alternative Titles
Full title
Safety and efficacy of desmoteplase given 3–9 h after ischaemic stroke in patients with occlusion or high-grade stenosis in major cerebral arteries (DIAS-3): a double-blind, randomised, placebo-controlled phase 3 trial
Authors, Artists and Contributors
Author / Creator
Albers, Gregory W, Prof
von Kummer, Rüdiger, Prof
Truelsen, Thomas, MD
Jensen, Jens-Kristian S, MSc
Ravn, Gabriela M, MSc
Grønning, Bjørn A, MD
Chabriat, Hugues, Prof
Chang, Ku-Chou, MD
Davalos, Antonio E, Prof
Ford, Gary A, Prof
Grotta, James, MD
Kaste, Markku, Prof
Schwamm, Lee H, Prof
Shuaib, Ashfaq, Prof
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1732839410
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1732839410
Other Identifiers
ISSN
1474-4422
E-ISSN
1474-4465
DOI
10.1016/S1474-4422(15)00047-2
