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The Genetic Evolution of Melanoma from Precursor Lesions

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The Genetic Evolution of Melanoma from Precursor Lesions

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1733188184

The Genetic Evolution of Melanoma from Precursor Lesions

About this item

Full title

The Genetic Evolution of Melanoma from Precursor Lesions

Author / Creator

Shain, A. Hunter , Yeh, Iwei , Kovalyshyn, Ivanka , Sriharan, Aravindhan , Talevich, Eric , Gagnon, Alexander , Dummer, Reinhard , North, Jeffrey , Pincus, Laura , Ruben, Beth , Rickaby, William , D’Arrigo, Corrado , Robson, Alistair and Bastian, Boris C

Publisher

United States: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2015-11, Vol.373 (20), p.1926-1936

Language

English

Formats

Articles

Publication information

Publisher

United States: Massachusetts Medical Society

Subjects

More information

Scope and Contents

Contents

Genetic analysis of melanomas from 37 patients sampled in 150 different areas showed that
BRAF
mutations were present from the first stages of tumor development, and progressively more malignant lesions showed acquisition of abnormalities in a predictable sequence.
Cancer arises through the accumulation of genetic alterations that lead to...

Alternative Titles

Full title

The Genetic Evolution of Melanoma from Precursor Lesions

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1733188184

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1733188184

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa1502583

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