Rif1 binds to G quadruplexes and suppresses replication over long distances
Rif1 binds to G quadruplexes and suppresses replication over long distances
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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ChIP-seq, biochemical and
in vivo
assays show that Rif1 binds G-rich motifs that can form G-quadruplex structures, thus regulating firing of proximal and distal DNA replication origins in fission yeast.
Rif1 regulates replication timing and repair of double-strand DNA breaks. Using a chromatin immunoprecipitation–sequencing method, we iden...
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Full title
Rif1 binds to G quadruplexes and suppresses replication over long distances
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TN_cdi_proquest_miscellaneous_1735334659
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1735334659
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.3102
