Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes
Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes
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Author / Creator
Sundaravel, Sriram , Duggan, Ryan , Bhagat, Tushar , Ebenezer, David L , Liu, Hui , Yu, Yiting , Bartenstein, Matthias , Unnikrishnan, Madhu , Karmakar, Subhradip , Liu, Ting-Chun , Torregroza, Ingrid , Quenon, Thomas , Anastasi, John , McGraw, Kathy L , Pellagatti, Andrea , Boultwood, Jacqueline , Yajnik, Vijay , Artz, Andrew , Le Beau, Michelle M , Steidl, Ulrich , List, Alan F , Evans, Todd , Verma, Amit and Wickrema, Amittha
Publisher
United States: National Acad Sciences
Journal title
Language
English
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Publisher
United States: National Acad Sciences
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Scope and Contents
Contents
Anemia is the predominant clinical manifestation of myelodysplastic syndromes (MDS). Loss or deletion of chromosome 7 is commonly seen in MDS and leads to a poor prognosis. However, the identity of functionally relevant, dysplasia-causing, genes on 7q remains unclear. Dedicator of cytokinesis 4 (DOCK4) is a GTPase exchange factor, and its gene maps...
Alternative Titles
Full title
Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes
Authors, Artists and Contributors
Author / Creator
Duggan, Ryan
Bhagat, Tushar
Ebenezer, David L
Liu, Hui
Yu, Yiting
Bartenstein, Matthias
Unnikrishnan, Madhu
Karmakar, Subhradip
Liu, Ting-Chun
Torregroza, Ingrid
Quenon, Thomas
Anastasi, John
McGraw, Kathy L
Pellagatti, Andrea
Boultwood, Jacqueline
Yajnik, Vijay
Artz, Andrew
Le Beau, Michelle M
Steidl, Ulrich
List, Alan F
Evans, Todd
Verma, Amit
Wickrema, Amittha
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1735335164
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1735335164
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1516394112
