Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemores...
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The role of epithelial-to-mesenchymal transition (EMT) in metastasis is a longstanding source of debate, largely owing to an inability to monitor transient and reversible EMT phenotypes
in vivo
. Here we establish an EMT lineage-tracing system to monitor this process in mice, using a mesenchymal-specific Cre-mediated fluorescent marker switch...
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Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
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TN_cdi_proquest_miscellaneous_1737477739
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1737477739
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature15748