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Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemores...

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemores...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1737477739

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

About this item

Full title

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2015-11, Vol.527 (7579), p.472-476

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The role of epithelial-to-mesenchymal transition (EMT) in metastasis is a longstanding source of debate, largely owing to an inability to monitor transient and reversible EMT phenotypes
in vivo
. Here we establish an EMT lineage-tracing system to monitor this process in mice, using a mesenchymal-specific Cre-mediated fluorescent marker switch...

Alternative Titles

Full title

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1737477739

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1737477739

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature15748

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