Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry
Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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A crosslinking-mass spectrometry strategy, including a new proteome database search engine called XlinkX, enables the identification of inter- and intra-protein cross-links in cell lysates on a proteome-wide scale.
We describe an integrated workflow that robustly identifies cross-links from endogenous protein complexes in human cellular lysates....
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Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry
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TN_cdi_proquest_miscellaneous_1738819215
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1738819215
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ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/nmeth.3603