Regulation of BRCA1 by protein degradation
Regulation of BRCA1 by protein degradation
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Publisher
Basingstoke: Nature Publishing
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Language
English
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Publisher
Basingstoke: Nature Publishing
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Scope and Contents
Contents
BRCA1, a tumor suppressor protein implicated in hereditary forms of breast and ovarian cancer, is transcriptionally regulated in a proliferation-dependent manner. In this study, we demonstrate a substantial role for proteolysis in regulating the BRCA1 steady-state protein level in several cell lines. N-acetyl-leu-leu-norleucinal (ALLN), an inhibito...
Alternative Titles
Full title
Regulation of BRCA1 by protein degradation
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TN_cdi_proquest_miscellaneous_17433337
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17433337
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1203068
